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Sulfheme formation mechanism and spectra analysis using QM/MM and TDDFT
(2018-05)
Since the 1863 discovery of a new green hemoglobin derivative called “sulfhemoglobin”, the
nature of its characteristic 618 nm absorption band and formation mechanism has been the subject of
several hypotheses. Many ...
Structural characterization of the oxygen reactive heamoglobins from the clam Lucina pectinata
(2014)
Hemoglobins comprise a challenging area of study within biochemical research. They play an
important physiological role in organisms, like oxygen transport and storage. Three hemoglobins were discovered in the ctenidia ...
Biomedical applications of nanotechnology : exploratory research on the use of one dimensional nanostructures
(2016)
Studies related to the use of nanoscaled materials in biomedical science and engineering research is at the forefront of research in medicine. Applied research in nanotechnology, particularly as related to medicine, is ...
Synthesis, formation mechanism and characterization of peroxide homemade explosives
(2013)
An important consideration in the area of homemade explosives, which are made from household products, is that it is difficult to control their production and use in terrorist activities. Therefore, security and defense ...
New ferrocene chemotherapeutic drugs and early detection of breast cancer using a nanostructured gold biosensor
(2015)
Three new ferrocene complexes were synthesized with 4-(1H-pyrrol-1-yl)phenol group appended to the cyclopentadienyl (Cp) rings. These are: 1,1’-4-(1H-pyrrol-1- yl)phenyl ferrocenedicarboxylate, (‘Fc-(CO2-Ph-4-Py)2’), ...
Remote infrared spectroscopy detection of highly energetic materials
(2015-12)
An Open-Path Standoff Detection System was designed using a telescope coupled to a EM27 Fourier Transform infrared spectrometer equipped with a mercury cadmium telluride (MCT) cryocooled detector. Samples of highly energetic ...
Synthesis, structural and cytotoxic studies of Metallocene-estrogen hormones conjugates for hormone dependent breast cancer application
(2019)
In this work we present the synthesis, characterization and application of a series of ferrocene-hormone conjugates at position 16 of the estrogen hormone moiety in order to develop a new class of metal-based therapeutic ...
Pathogenic bacteria detection by coupled water-soluble Cd- and Zn-based fluorescent nanocrystals
(2019-05-15)
Semiconductors quantum dots are considered very promising candidates for bio-imaging, microorganism detection and diagnosis applications, among others, because of their tunable optical properties and good optical stability ...
Enhanced singlet oxygen from Zno quantum dots nanoparticles derivatives for Photodynamic Therapy (PDT) and cytotoxic activity in chronic lymphocytic leukemia (CLL) tumor cells
(2015)
The generation of singlet oxygen (SO) in presence of specific photosensitizers (PS) or semiconductor quantum dots and its application in photodynamic therapy is of great interest to develop cancer therapies with no need ...
Global and local structural analysis of the sulfheme complex: A role in the decrease of myoglobin functionality
(2016)
When the human body is exposed to high concentration of hydrogen sulfide (H2S, recently identified as a signaling gas), a rare type of anemia called sulfhemoglobinemia is developed. This condition is triggered by the ...