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Near infrared spectroscopic transmission measurements for pharmaceutical powder mixtures and theory of sampling (TOS) applied in pharmaceutical industry quality control (Qc) practices
(2015)
This thesis presents two projects that involve the implementation of near infrared spectroscopy. NIR spectroscopy is a fast and non-destructive spectroscopy that in combination with multivariate analysis is a very useful ...
New ferrocene chemotherapeutic drugs and early detection of breast cancer using a nanostructured gold biosensor
(2015)
Three new ferrocene complexes were synthesized with 4-(1H-pyrrol-1-yl)phenol group appended to the cyclopentadienyl (Cp) rings. These are: 1,1’-4-(1H-pyrrol-1- yl)phenyl ferrocenedicarboxylate, (‘Fc-(CO2-Ph-4-Py)2’), ...
Remote infrared spectroscopy detection of highly energetic materials
(2015-12)
An Open-Path Standoff Detection System was designed using a telescope coupled to a EM27 Fourier Transform infrared spectrometer equipped with a mercury cadmium telluride (MCT) cryocooled detector. Samples of highly energetic ...
Exploring Centrin targets: KRR1, and the Centrin-SFI1p21 complex salt-bridge interaction
(2015)
Centrins are small calcium binding proteins and ubiquitous centrosome components. Centrins play a fundamental role in the structure and function of centrioles, basal bodies, primary cilia and the microtubule-organizing ...
Enhanced singlet oxygen from Zno quantum dots nanoparticles derivatives for Photodynamic Therapy (PDT) and cytotoxic activity in chronic lymphocytic leukemia (CLL) tumor cells
(2015)
The generation of singlet oxygen (SO) in presence of specific photosensitizers (PS) or semiconductor quantum dots and its application in photodynamic therapy is of great interest to develop cancer therapies with no need ...