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Development of targeted formulations for the delivery of a cytochrome c-based drug for application in cancer therapy
(2021-05-13)
The progression of a cell toward apoptosis, upon cellular stress, is accompanied by a set of characteristic events which includes permeabilization of the mitochondrial outer membrane and release of cytochrome c into the ...
Cross-linked cytochrome c-based nanoparticles for targeted and controlled cancer therapy
(2022-05-06)
Cancer is a major public health problem worldwide and is the second leading cause of death in the United States. The persistent need to develop cancer therapeutics with improved safety and efficacy provides constant fuel ...
Bisphosphonate-based coordination complexes and immobilization thereof in titanium dioxide nanoparticles
(2022-05-02)
Coordination complexes (CCs), as well as inorganic nanoparticles, present several advantages towards nanotechnology-based cancer therapy applications. Both types of materials provide stability, specificity, low cytotoxicity, ...