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Design of composite protein microcrystals for the sustained oral delivery of antigens
(2015)
Oral immunization is a promising method to decrease access of allergens and pathogens to the body. Oral delivery of antigens is challenged by the anatomical conditions of the gastrointestinal tract, such as degradation by ...
Development of optimized therapeutic platforms for magnetic fluid hyperthermia in adjuvant cancer therapies
(2018-05)
Magnetic Fluid Hyperthermia (MFH) has a great potential as an adjuvant in cancer therapy, enhancing the
effects of antineoplastic agents, sensitizing resistant cancers and reducing undesired side effects. When
compared ...
Enhanced potentiation of anticancer drugs using magnetic fluid hyperthermia (MFH): In vitro and in vivo studies
(2014)
Clinical studies have demonstrated the effectiveness of combined hyperthermia and anticancer drug treatments. Challenges related to effective heat transfer have limited its clinical application. The use of magnetic fluids ...
Use of crosslinked hydrogels for the control of macromolecular crystallization
(2012)
Crosslinked hydrogels in protein crystallization is an area of continuous growth. The counterdiffusion technique is a novel method for the crystallization of proteins, which entails the minimization of convection effects, ...
Encapsulation of particles in crosslinked hydrogel networks: particles distribution optimization
(2010)
Particle encapsulation in polymer systems has been used in several industrial applications in the biomedical and pharmaceutical fields. The main challenge in particle encapsulation is to obtain a homogeneous particle ...