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Real-time monitoring of pharmaceutical formulations within continuous process units for tablet manufacturing
(2021-03-18)
This dissertation describes the advancements in Process Analytical Technology (PAT) through developing and implementing strategies for real-time monitoring of drug concentrations in flowing powder blends, analyzing the ...
Effect of operational and design parameters on the early stages of high shear wet granulation processes
(2014)
The development of new technologies, active ingredients and regulatory initiatives, has increased the need for a scientific understanding of the pharmaceutical manufacturing processes. In this context, solid dosage forms ...
Effect of initial formulation conditions, process parameters and equipment design on wet granulation
(2020-07-24)
Ease of administration and handling are some of the reasons to keep solid oral dosage forms as the presentation of predilection for today’s medicines. Today, pharmaceutical companies are looking for more efficient processes ...
Improving continuous manufacturing process reliability through feeding control system
(2018-12-12)
Continuous manufacturing processes are complex systems composed of multiple unit operations where process variables and material properties interaction allow the development of soft PAT sensors. Hence, this study was focused ...