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Now showing items 41-50 of 141
Design of composite protein microcrystals for the sustained oral delivery of antigens
(2015)
Oral immunization is a promising method to decrease access of allergens and pathogens to the body. Oral delivery of antigens is challenged by the anatomical conditions of the gastrointestinal tract, such as degradation by ...
Hierarchical porous carbon-zeolite composites materials for the adsorption of contaminants of emerging concern from water
(2021-03-23)
The steady and unnoticed rise of contaminants of emerging concern (CECs) into different water sources results in a tremendous challenge regarding its efficient, systematic, and coherent mitigation. Its recalcitrant presence, ...
Synthesis and characterization of magnetic nanoparticles for use as sensors
(2009-06)
A comprehensive study of physical and magnetic properties of cobalt substituted ferrite and magnetite nanoparticles synthesized by thermal-decomposition was carried out. Initially, a systematic study of the effect of ...
Optimization of drying-end-points measurements for the automation of a fluidized-bed dryer using FT-NIR sprectroscopy
(2004)
Automatic control of a fluidized-bed drying process depends on the availability of
an in-line sensor to provide accurate measurements of product moisture content. Nearinfrared
(NIR) spectroscopy technology provides a ...
Real-time monitoring of pharmaceutical formulations within continuous process units for tablet manufacturing
(2021-03-18)
This dissertation describes the advancements in Process Analytical Technology (PAT) through developing and implementing strategies for real-time monitoring of drug concentrations in flowing powder blends, analyzing the ...
Automation of a fluid bed dryer using multi-variant near infrared spectra and model predictive control
(2010)
The Fluidized Bed Dryer (FBD) is a common unit used in the pharmaceutical industry for its unique advantages when working with powders. With recent development in technology and environmental awareness, a desire to optimize ...
Evaluation of NIR, FTIR and Raman spectroscopies as monitoring techniques for recombinant GFP protein production in fed-batch cultures of Escherichia coli
(2008)
The expression of green fluorescent protein (GFP) was induced and monitored in fed-batch cultures of a genetically-engineered Escherichia coli strain. This recombinant E. coli is commercially available (Bio-Rad pGLO kit), ...
A new mixing rule in the modeling of the solubility of solids in supercritical fluids
(2006)
Currently, supercritical-fluid technology in the pharmaceutical and microelectronics industries is increasingly applied to solve difficult processing problems. The solubility of a solute in the supercritical fluid is the ...
Oil accumulation via Chlorella species using carbon sources from waste
(2009-12)
One of the global issues acquiring significant attention these days is related to energy supply and demand. The irreversible decrease of fossil fuels left to supply energy and the greenhouse gases increase in the atmosphere ...
Advanced process control of a fluid bed dryer granulator using near infrared sensing technology: An educational tool
(2020-12-11)
In this work, the design of an advanced process control strategy for a batch fluid bed dryer was achieved. This accomplishment will become an educational tool for the Center for Pharmaceutical Development and Learning ...