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Affecting intracellular iron and copper via transmetalation and study of drug delivery systems to improve the specificity of Ti(IV)-based anticancer compounds
(2022-04-27)
Cancer is the principal cause of death globally, and research and how it works have become crucial. Iron (Fe) and Copper (Cu) are essential metals present in many critical biological processes in the human body. These ...
The potential of natural polysaccharides: chemical approaches for bone tissue regeneration
(2021-11-16)
There are approximately 44 million people in the United States alone who suffer from diseases that cause bone density loss; and as life expectancy increases, so do the probabilities of being inflicted with such diseases. ...
Cross-linked cytochrome c-based nanoparticles for targeted and controlled cancer therapy
(2022-05-06)
Cancer is a major public health problem worldwide and is the second leading cause of death in the United States. The persistent need to develop cancer therapeutics with improved safety and efficacy provides constant fuel ...
Transmission Raman Spectrometer design for the detection of opioids, concealed chemicals, and biological threats
(2021-07-08)
Raman spectroscopy (RS) is an excellent tool for quantitative and qualitative analysis that can be used to detect and characterize different types of substances. Transmission Raman Spectroscopy (TRS) has been used in ...
Synthesis of novel ferrocene complexes with androgens vectors, biological activity and their interactions with proteins
(2020-12-11)
Four novel complexes were synthetized by aldol condensation reaction and characterized by different spectroscopic techniques using ferrocenecarboxaldehyde as starting material, and using the hormones ( 3α-hydroxy ...
Detection and discrimination of high explosives on human hair by Raman scattering
(2020-05-29)
High explosives (HE) represent a high risk to the safety and health of the general population. Therefore, there is an ongoing demand for methods of analysis with limits of detection at trace levels for these hazardous ...
Flavonoid-ferrocene conjugate as new treatment for breast cancer
(2021-07-08)
Research in drug development for breast cancer treatment has been crucial, since traditional treatments have been associated with neurotoxicity and nephrotoxicity. Previous studies showed that when ferrocene is combined ...
Quantum cascade laser-grazing angle spectroscopy detection of high explosives deposited on various substrates using air spray
(2020-04-19)
The mid-infrared (MIR) laser reflectance of samples of high explosives (HEs) deposited on reflective and matte substrates using spray deposition was measured and used to generate multivariate (MVA) models for the analysis ...
Crystal structures of hemeproteins: Sulf and H2S myoglobin derivatives and Lucina pectinata Oxy (HbII-HbIII) and Oxy (HbIII-HbIII) systems
(2020-04-21)
As a gasotransmitter, hydrogen sulfide (H2S) biochemistry in humans is of pivotal importance. One relevant reaction of H2S in our bodies is its interaction with hemeproteins. The threshold of its beneficial/harmful effects ...
TNT and MO photodegradation in deionized and salt waters with visible light assisted by photoactivation of modified TiO2
(2020-05-22)
The release of munitions during military combat events or training exercises represents an alarming situation to the marine environment. Since nitroaromatic compounds (NACs) that are released from these weapons remain in ...