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Effects of Lipid-Analog Detergent Solubilization on the Functionality and Lipidic Cubic Phase Mobility of the Torpedo californica Nicotinic Acetylcholine Receptor
(The Journal of Membrane Biology, 2012)
Over the past three decades, the Torpedo californica nicotinic acetylcholine receptor (nAChR) has
been one of the most extensively studied membrane protein systems. However, the effects of
detergent solubilization on ...
Uncovering the lipidic basis for the preparation of functional nicotinic acetylcholine receptor detergent complexes for structural studies.
(Nature / Scientific Reports, 2016-09-19)
This study compares the lipid composition, including individual phospholipid molecular species of solubilized nAChR detergent complexes (nAChR-DCs) with those of the bulk lipids from their source, Torpedo californica (Tc) ...
The α7-nicotinic Receptor is Upregulated Inimmune Cells from HIV-seropositive Women: Consequences to the Cholinergic Anti-inflammatory Response.
(Nature Publishing Group, 2015-12-11)
Antiretroviral therapy partially restores the immune system and markedly increases life expectancy of HIV-infected patients. However, antiretroviral therapy does not restore full health. These patients suffer from poorly ...
Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments
(The Journal of Membrane Biology, 2008-05)
The nicotinic acetylcholine receptor (nAChR) of Torpedo electric rays has been extensively
characterized over the last three decades. However, the molecular mechanisms by which detergents
influence membrane protein ...
Biophysical and Ion Channel Functional Characterization of the Torpedo Californica Nicotinic Acetylcholine Receptor in Varying Detergent-Lipid Environments
(Springer-Verlag, 2009-05-01)
The nicotinic acetylcholine receptor (nAChR) of Torpedo electric rays has been extensively characterized over the last three decades. However, the molecular mechanisms by which detergents influence membrane protein stability ...
Effects of Lipid-Analog Detergent Solubilization on the Functionality and Lipidic Cubic Phase Mobility of the Torpedo Californica Nicotinic Acetylcholine Receptor
(Springer International Publishing AG. Part of Springer Nature., 2011-10)
Over the past three decades, the Torpedo californica nicotinic acetylcholine receptor (nAChR) has been one of the most extensively studied membrane protein systems. However, the effects of detergent solubilization on nAChR ...
Potential role of caveolin-1-positive domains in the regulation of the acetylcholine receptor’s activatable pool : implications in the pathogenesis of a novel congenital myasthenic syndrome
(National Library of Medicine. National Center for Biotechnology Information, 2008-06)
Cholesterol modulates the plasmalemma’s biophysical properties and influences the function and trafficking of membrane proteins. A fundamental phenomenon that remains obscure is how the plasmalemma’s lipid composition ...
The α7‐nicotinic receptor is upregulated in immune cells from HIV‐seropositive women : consequences to the cholinergic anti‐inflammatory response
(Australasian Society for Immunology, 2015-12-11)
Antiretroviral therapy partially restores the immune system and markedly increases life expectancy of HIV-infected patients. However, antiretroviral therapy does not restore full health. These patients suffer from poorly ...
The alpha7-nicotinic receptor contributes to gp120-induced neurotoxicity : implications in HIV-associated neurocognitive disorders
(Springer, 2018-01-29)
Currently, there are no specific therapies to treat HIV-1 associated neurocognitive disorders (HAND). The HIV-1 envelope, gp120, induces neuropathological changes similar to those in HAND patients; furthermore, it triggers ...