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Ubiquitin-Proteasome System Components are Up-Regulated During Intestinal Regeneration
(John Wiley & Sons, Inc., 2012-04)
The ubiquitin proteasome system (UPS) is the main proteolytic system of cells. Recent evidence suggests that the UPS plays a regulatory role in regeneration processes. Here we explore the possibility that the UPS is involved ...
Transcriptomic Changes During Regeneration of the Central Nervous System in an Echinoderm.
(BioMed Central (BMC) owned by Springer Nature., 2014-05-12)
Background:
Echinoderms are emerging as important models in regenerative biology. Significant amount of data
are available on cellular mechanisms of post-traumatic repair in these animals, whereas studies of gene expression ...
Heterogeneous Generation of New Cells in the Adult Echinoderm Nervous System
(Frontiers Media S.A., 2015-09-22)
Adult neurogenesis, generation of new functional cells in the mature central nervous system (CNS), has been documented in a number of diverse organisms, ranging from humans to invertebrates. However, the origin and evolution ...
Calbindin-D32k Is Localized to a Subpopulation of Neurons in the Nervous System of the Sea Cucumber Holothuria glaberrima (Echinodermata).
(Public Library of Science (PLOS), 2012-03-07)
Members of the calbindin subfamily serve as markers of subpopulations of neurons within the vertebrate nervous system. Although markers of these proteins are widely available and used, their application to invertebrate ...
Expression of Wnt9, TCTP, and Bmp1/Tll in Sea Cucumber Visceral Regeneration.
(Elsevier B.V., 2012-01)
We employ non-radioactive in situ hybridization techniques, which combine good tissue morphology preservation with high sensitivity of transcript detection, to map gene expression in the regenerating digestive tube of the ...
Characterization of Proteolytic Activities During Intestinal Regeneration of the Sea Cucumber, Holothuria Glaberrima
(UBC Press, 2012)
Proteolysis carried out by different proteases control cellular processes during development and regeneration. Here we investigated the function of the proteasome and other proteases in the process of intestinal regeneration ...
Cell Dedifferentiation and Epithelial to Mesenchymal Transitions During Intestinal Regeneration in H. Glaberrima.
(BioMed Central, 2011)
Background:
Determining the type and source of cells involved in regenerative processes has been one of the
most important goals of researchers in the field of regeneration biology. We have previously used several ...
Radial Glial Cells Play a Key Role in Echinoderm Neural Regeneration.
(STM (Science, Technology and Medicine) publisher, 2013)
Background:
Unlike the mammalian central nervous system (CNS), the CNS of echinoderms is capable of fast and
efficient regeneration following injury and constitutes one of the most promising model systems that can ...
Holothurian Nervous System Diversity Revealed by Neuroanatomical Analysis.
(Public Library of Science (PLOS), 2016-03-17)
The Echinodermata comprise an interesting branch in the phylogenetic tree of deutero-
stomes. Their radial symmetry which is reflected in their nervous system anatomy makes
them a target of interest in the study of nervous ...
Changes in Holothurian Coelomocyte Populations Following Immune Stimulation with Different Molecular Patterns
(Elsevier Ltd., 2010-08)
Echinoderms possess a variety of cells populating the coelomic fluid; these cells are responsible for mounting defense against foreign agents. In the sea cucumber Holothuria glaberrima, four different coelomocyte types ...