Search
Now showing items 1-10 of 19
Cardiac and renal effects of atrasentan in combination with enalapril and paricalcitol in uremic rats
(Karger Publishers Open Access, 2014-09)
Background/aims: The search for new therapies providing cardiorenal protection in chronic kidney disease (CKD) has led to treatments that combine conventional renin-angiotensin-aldosterone-system inhibitors with other drugs ...
Allelic frequency of PAR-2 in the Puerto Rican population a possible insight to asthma prevalence.
(University of Puerto Rico at Ponce, 2007)
The Human Genome Project has sequenced the genetic complement of our species: the DNA. Such sequencing was performed using DNA randomly collected from individuals of diverse ethnicity backgrounds. This aleatory selection ...
Effects of antioxidant n-acetylcysteine against paraquat 1-induced oxidative stress tissues of mice.
(International Journal of Sciences: Basic and Applied Research (IJSBAR), 2016)
Paraquat (PQ) is a commonly used herbicide that induces oxidative stress via reactive oxygen species (ROS) generation. This study aimed to investigate the effects of the antioxidant N-acetylcysteine (NAC) against PQ-induced ...
Aging increases mitochondrial DNA damage and oxidative stress in liver of rhesus monkeys
(Elsevier, 2012-01)
While the mechanisms of cellular aging remain controversial, a leading hypothesis is that mitochondrial oxidative stress and mitochondrial dysfunction play a critical role in this process. Here, we provide data in aging ...
Active mode remote infrared spectroscopy detection of TNT and PETN on aluminum substrates
(Hindawi Publishing Corporation, 2017-03)
Two standoff detection systems were assembled using an infrared telescope coupled to a Fourier transform infrared spectrometer, a cryocooled mercury-cadmium telluride detector, and a telescope-coupled midinfrared excitation ...
Adiponectin expression and the cardioprotective role of the vitamin D receptor activator paricalcitol and the angiotensin converting enzyme inhibitor enalapril in ApoE-deficient mice
(SAGE Publications Open Access, 2014-12)
Background—Coronary heart disease (CHD) is the number one cause of death in the US. The adipokine adiponectin has been studied intensively for presenting and inversed association with almost every stage of CHD. For instance, ...
SNPs in the lysyl oxidase-like protein 4 (LOXL4) and complement component 3 (C3) genes are associated with increased risk for endometriosis and endometriosis-associated Infertility
(Elsevier, 2011-08)
This study was conducted to assess genetic associations to endometriosis in a Puerto Rican population. Significant differences in allelic frequencies and genotype distribution of genetic variants in LOXL4 and C3 were ...
Effect of hydroxychloroquine and characterization of autophagy in a mouse model of endometriosis
(Nature Publishing Group, 2016-01-14)
In endometriosis, the increased survival potential of shed endometrial cells (which normally undergo anoikis) is suggested to promote lesion development. One mechanism that may alter anoikis is autophagy. Using an autophagic ...
Patients’ report on how endometriosis affects health, work, and daily life
(Elsevier, 2010-05)
The objective of this study was to assess the burden of endometriosis by obtaining Patient Reported Outcome (PRO) data describing the experience of living with this disease. Survey data from one hundred and seven women ...
Quantum cascade laser (QCL) spectroscopy, explosives detection, classical least squares (CLS), cotton fabrics, discriminant analysis (DA), highly energetic materials (HEMs)
(2017)
Quantum cascade laser spectroscopy was used to detect the presence of residues of highly energetic materials (HEMs) on cotton fibers. The discrimination of the vibrational signals of HEMs from a highly mid-infrared (MIR) ...