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SNPs in the lysyl oxidase-like protein 4 (LOXL4) and complement component 3 (C3) genes are associated with increased risk for endometriosis and endometriosis-associated Infertility

dc.contributor.authorRuiz, Lynnette A.
dc.contributor.authorDutil, Julie
dc.contributor.authorRuiz, Abigail
dc.contributor.authorFourquet, Jessica
dc.contributor.authorAbac, Sonia
dc.contributor.authorLaboy, Joaquín
dc.contributor.authorFlores, Idhaliz
dc.date.accessioned2017-06-22T12:29:10Z
dc.date.available2017-06-22T12:29:10Z
dc.date.issued2011-08
dc.identifier.citationRuiz LA, Dutil J, Ruiz A, et al. SNPs in the Lysyl Oxidase-like Protein 4 (LOXL4) and Complement Component 3 (C3) genes are Associated with Increased Risk for Endometriosis and Endometriosis-Associated Infertility. Fertility and sterility. 2011;96(2):512-515. doi:10.1016/j.fertnstert.2011.06.001.en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143268/pdf/nihms301553.pdf
dc.identifier.urihttp://hdl.handle.net/11721/1648
dc.description.abstractThis study was conducted to assess genetic associations to endometriosis in a Puerto Rican population. Significant differences in allelic frequencies and genotype distribution of genetic variants in LOXL4 and C3 were documented in patients with endometriosis-associated infertility vs controls, and in patients with endometriosis vs controls, respectively, and in women having the risk genotype at both SNPs, the estimated risk for endometriosis nearly doubled.en_US
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.subjectendometriosis/geneticsen_US
dc.subjectsingle nucleotide polymorphisms (SNPs)en_US
dc.subjectlysyl oxidase-like 4en_US
dc.subjectcomplement factor 3en_US
dc.subjectLOXL4en_US
dc.subjectC3en_US
dc.subjectinfertility/geneticsen_US
dc.subjectgenetic variantsen_US
dc.subjectgenetics
dc.titleSNPs in the lysyl oxidase-like protein 4 (LOXL4) and complement component 3 (C3) genes are associated with increased risk for endometriosis and endometriosis-associated Infertilityen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.fertnstert.2011.06.001en_US
dc.local.DepartmentDepartment of Biologyen_US
dc.local.FacultySelect from the list belowen_US
dc.contributor.campusUniversity of Puerto Rico at Ponce


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