Theses & Dissertations
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Los trabajos de investigación o proyectos que fueron aprobados por profesores para obtener un grado bachillerato, maestría o doctorado.
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¿Homosexual, trastornado o disfórico? : Construcciones de la sexualidad, identidad y el género desde el Manual Diagnóstico y Estadístico de los Trastornos Mentales
(2022-04-29)El discurso médico psiquiátrico ha sido instrumental en la conceptualización, producción y psicopatologización de las representaciones dominantes de lo que son los sujetos transgénero. Por tal razón, en esta investigación ... -
Studies of structural, electrical and ferroelectric properties of rare-earth substituted bismuth titanate-films.
(2007-05)In the present research, Bi<sub>4</sub>Ti<sub>3</sub>O<sub>12</sub> (BTO) and its rare earth (La, Nd, Sm, Gd)-substituted derivative thin films were synthesized using a sol-gel method and were systematically investigated. ... -
Intracellularly dissolving chromophore-decorated protein-based nanoparticles for photodynamic cancer therapy.
(2016-07)Cancer has proven to be extremely complex to treat and cure due to its heterogeneity. Current treatments rely mainly on chemotherapeutic drugs, which typically result in multidrug resistance and the generation of additional ... -
Deep learning for animal audio classification - a foundational approach
(2022-06-10)Despite impressive successes in computer vision, deep learning has made more limited progress for audio data, mostly in voice recognition and speech processing. Furthermore, most such work has depended on spectrograms and ... -
The impact of land use and land cover changes and human dynamics in Jobos Bay National Estuarine Research Reserve in Puerto Rico.
(2022-06-13)The Jobos Bay National Estuarine Research Reserve has been facing land changes in its watershed since the 1970s, particularly in agriculture activities and urban growth. The Jobos Bay Watershed (JBW) is historically ... -
Decreased hyperpolarization-activated cation current (I<sub>h</sub>): a response mechanism to reduce cocaine-induced excitability in VTA DA neurons.
(2022-06-09)The hyperpolarization-activated cation current (I<sub>h</sub>) is a determinant of intrinsic excitability in dopaminergic neurons (DA) of the ventral tegmental area (VTA). I<sub>h</sub> is a slowly activating cation inward ... -
Synthesis, characterization and structural properties of fluorinated metal phthalocyanine chemiresistors for environmental parts-per-billion detection of toxic gases
(2022-05-13)The doctoral thesis presented herein starts with an outline of the rich chemistry of MPc semiconducting platforms, presented in Chapter 1. The synthesis of numerous phthalocyanine semiconducting platforms is described in ... -
Mechanisms of alcohol-induced sleep dysregulation in <em>Drosophila melanogaster</em>
(2022-06-06)Alcohol consumption is known to disturb a variety of biological processes that affect normal physiological function. In the nervous system, alcohol is generally known to affect several molecular targets leading to an overall ... -
ST-distributive and ST-modular lattices
(2022-04-26)This thesis proposes two new classes of lattices: <em>ST</em>-distributive and <em>ST</em>-modular lattices. The idea is to define relative distributive and modular properties that are satisfied by some elements over two ... -
A cross-talk between Transient Receptor Potential Vanilloid 1 and Cannabinoid Receptor 1 within the limbic system regulates depression and stress-induced anxiety-like behavior in rats.
(2022-05-08)Clinical studies provide strong evidence that stress is an environmental risk factor that can trigger the onset of several neuropsychiatric disorders such as anxiety and depression in humans. Pre-clinical evidence suggests ... -
Assessing the impact of coastal processes on archaeological sites in Loíza Puerto Rico: integrating Geographic Information System (GIS), remote sensing, and numerical modeling techniques
(2022-05-09)Archaeological sites are a part of cultural heritage that is threatened by accelerated climate change. This research evaluated climate hazard impacts on archaeological sites in Loíza, Puerto Rico. The main methods applied ... -
Effect of critical material attributes and process parameters on polymorph selection in crystalline solid dispersions
(2022-04-29)The inadvertent occurrence of polymorphic phase transformations during the formulation of crystalline solid dispersions (CSDs) hinders the implementation of continuous polymer-based formulation processes. Although polymorphic ... -
Ecophysiological responses of plant functional types to environmental conditions in a coastal urban wetland, Ciénaga Las Cucharillas in Northeastern Puerto Rico
(2022-05-20)Coastal wetlands are influenced by their terrestrial-marine connectivity. Anthropogenic changes in these ecosystems have added additional stressors to plants, like the presence of heavy metals in soils. We evaluated ... -
Bisphosphonate-based coordination complexes and immobilization thereof in titanium dioxide nanoparticles
(2022-05-02)Coordination complexes (CCs), as well as inorganic nanoparticles, present several advantages towards nanotechnology-based cancer therapy applications. Both types of materials provide stability, specificity, low cytotoxicity, ... -
Pt-based electrocatalysts for energy conversion reactions: an electrochemical <em>In situ</em> X-ray absorption spectroscopy approach in alkaline medium
(2022-04-26)It is well established that energy use via fossil fuels can be related to global warming; this renders higher atmospheric carbon dioxide levels. The migration to renewable energy technologies has proven to be an alternative ... -
Desarrollo socioemocional e interacción diádica: una muestra de bebés prematuros nacidos de madres puertorriqueñas con sintomatología depresiva y ansiosa
(2022-05-26)Introducción: Las madres en la etapa perinatal pueden presentar síntomas elevados de ansiedad y depresión en comparación a la población general. Estos síntomas pudieran empeorar cuando las madres tienen un bebé que nace ... -
Protein-DNA interactions of oxidative-stress transcription factors OxyR1 and OxyR2 in <em>Aliivibrio fischeri</em>
(2022-05-11)Transcription factors (TFs) are regulatory proteins that bind tightly to specific DNA sequences 15-20 base pairs long. Being sequence-specific DNA-binding proteins, TFs bear the key to the cellular state and control how ... -
Empleabilidad de personas con antecedentes penales en Puerto Rico: perspectiva de los patronos
(2022-04-27)El objetivo principal del estudio fue conocer la perspectiva de los patronos en Puerto Rico sobre la empleabilidad de las personas con antecedentes penales. Se realizaron entrevistas semiestructuradas sobre el proceso de ... -
Phytoestrogen coumestrol as an anti-cancer therapy against triple-negative inflammatory breast cancer
(2022-05-25)Coumestrol (Cou) is a phytoestrogen present in soy and clover sprouts which is structurally similar to estrogen (E2) and has a cytotoxic effect in breast cancer cell lines. Nevertheless, the molecular mechanism by which ... -
The contribution of female mate choice and pupal mating to the reproductive isolation between the butterflies <em>Heliconius erato</em> and <em>Heliconius himera</em>
(2022-03-17)Alternative mating tactics, mutual mate choice, and multiple mating cues can contribute to reproductive isolation but are rarely all addressed in case studies of speciation. Here, we dissected the behavioral components of ...