Theses & Dissertations
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Los trabajos de investigación o proyectos que fueron aprobados por profesores para obtener un grado bachillerato, maestría o doctorado.
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Maintaining neural function: the role of Gooseberry, the Pax 3/7 homologue in controlling synaptic growth, plasticity, and stability
(2019-12-09)Although neurons are long-lived cells little is known about the mechanisms responsible for maintaining their properties and cellular stability. Here, we investigate the pair-rule transcription factor Gooseberry (Gsb), ... -
Variation of bio-acoustic signals and vocal apparatus anatomy (larynx) of <em>Eleutherodactylus coqui </em>and <em>Eleutherodactylus antillensis</em> in Puerto Rico
(2019-12-06)The current position of the islands that make up the Caribbean Region, such as the Greater Antilles, the Lesser Antilles and the Bahamas, was a very dynamic one. Our interest in understanding the evolution of anuran ... -
Post-natal deficiency of omega-3 fatty acids: its role on cocaine-seeking behaviors and drug withdrawal severity.
(2019-08-21)Adolescence is a transitional stage characterized by unique neurobiological changes in the brain. The brain's maturation during this stage, particularly in the frontal cortex and the limbic system, is responsible for ... -
Comparative genomic analysis of proteome reduction in the apicomplexans
(2020-05-16)Apicomplexans are alveolate parasites which include <em>Plasmodium falciparum</em>, the main cause of malaria, one of the world’s biggest killers from infectious disease. Apicomplexans are characterized by a reduction ... -
Influence of climatic variables and biological control agents (nematodes) on the distribution and survival of the coffee berry borer, <em>Hypothenemus hempei</em>, in Puerto Rico
(2019-12-09)Coffee is the second largest export product of developing countries and is one of the ten most important cultivated crops in Puerto Rico, especially in the mountainous region. The coffee berry borer (CBB) <em>Hypothenemus ... -
Identification and characterization of Npl3 as a novel prion like protein and its function in the regulation of gene expression in <em>Saccharomyces cerevisiae</em>
(2019-12-06)Nuclear protein localization-3 (Npl3) is a highly dynamic protein involved in mRNA biogenesis. Previous studies showed that the <em>npl3-95</em> allele encodes a protein that can aggregate into high molecular weight ... -
The role of NMDA receptors in the aggressive phenotype of inflammatory breast cancer (IBC).
(2022-07-26)Inflammatory Breast Cancer (IBC) is the most aggressive and lethal type of breast cancer. In most cases, the presence of a solid tumor is replaced by swelling, redness, and skin changes, which results in the misdiagnosis ... -
Molecular mechanisms underlying temperature-dependent synaptic growth at the <em>Drosophila melanogaster</em> neuromuscular junction
(2023-08-17)There is clear evidence that Earth's temperature is rising at an unprecedented rate. While consequences on ecosystems are being extensively studied, little is known about the consequences of temperature on the nervous ... -
Applications of two-dimensional tungsten disulfide and boron nitride nanosheets in self-powered photodetectors and memory devices
(2023-08-22)Since single-layer graphene was isolated from highly-oriented pyrolytic graphite in 2004, it led to the beginning of a new revolution in materials science due to its many applications in nano-electronic device technology. ... -
Studies on multifunctional materials applied to energy storage
(2023-08-07)Structure, phonon, and energy storage density in Sr<sup>2+</sup>-substituted lead-free ferroelectric Ba<sub>1-;x</sub>Sr<sub>x</sub>TiO<sub>3</sub> (BST<sub>x</sub>) for compositions x= 0.1, 0.3, and 0.7 were investigated ... -
Synthesis and characterization of cathode materials for lithium-sulfur batteries
(2023-07-31)Lithium-sulfur (Li-S) batteries have attracted considerable interest as next-generation high-density energy storage devices. However, their practical applications are limited due to rapid capacity fading when cycling cells ... -
Synthesis and evaluation of novel heterocyclic ferrocenyl chalcone hybrids as possible anticancer and antioxidant agents
(2023-06-02)Breast cancer is currently the most diagnosed cancer in women, with 287,850 new cases estimated in 2022, as reported by the American Cancer Society. Therefore, finding an effective treatment for this disease is imperative. ... -
Molecular mechanisms of intestinal organogenesis: A transcriptomic approach
(2023-06-02)Organogenesis is a process normally reserved for developing organisms, however, some adult organisms are capable of such a feat. Adult sea cucumbers, in the highly regenerative clade Echinodermata, can undergo intestinal ... -
Evaluation of the stressors for the Puerto Rican racer (<em>Borikenophis portoricensis</em>: Colubridae) populations
(2013-05-31)Worldwide, ~3,400 species of snakes are recognized. These reptiles are an important component of tropical and temperate ecosystems because of their role as high level predators. Many snake species worldwide are threatened ... -
Titanium oxide nanoparticles in the freshwater ecosystem: <em>Atya lanipes</em> shrimp as a nanotoxicological model
(2023-05-16)This dissertation specializes in studying and determining the environmental concentrations of an emerging pollutant of which we do not fully know, titanium oxide nanoparticles (TiO<sub>2</sub> NPs). Although we are aware ... -
Analysis of population size and food preference of <em>Pterygoplichthys multiradiatus</em>: focus on microplastics in streams with different human impacts
(2023-05-31)The pollution and accumulation of plastic in the environment, along with its mass production, has grown significantly in recent decades. Plastic can be very persistent due to its durability, and strength. Furthermore, they ... -
Assessing the performance of polymer/enzyme structures for liquid molecular separations
(2022-11-04)Inadequate wastewater infrastructure has led to the development of alternative, more efficient, sustainable separation methods. The thesis research focused on developing separation material for liquid molecular separations ... -
Unraveling the role of RNA Binding Protein with Multiple Splicing (RBPMS) in ovarian cancer cells
(2023-01-17)RNA-Binding Protein with Multiple Splicing (RBPMS) is member of a family of proteins that bind to nascent RNA transcripts and regulate their splicing, localization, and stability. Evidence indicates that RBPMS controls the ... -
A socioecological approach using watershed health and social vulnerability in a headwater sub-basin of the Río Grande de Arecibo
(2023-05-25)The Río Grande de Arecibo (RGA) Watershed is a crucial source of water through the North Coast Super Aqueduct for the residents of the Island of Puerto Rico, including those living in the San Juan metropolitan area. It is ... -
From nano to macro: A sustainable and holistic approach to improve water quality in changing environment
(2023-07-24)The increasing human population and associated demands for natural resources presents a direct challenge to the quality and quantity of potable water. Anthropogenic activities such as industrialization, agriculture, and ...
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