This dissertation focuses on the development of real-time spectroscopic methods to investigate the sources of variation in dynamic processes using variographic analysis and accomplish material traceability for continuous ...

Pharmaceutical companies are responsible for the development of their own blend uniformity specifications and guidelines to assure uniformity and homogeneity. Blend uniformity is a critical in the manufacturing of solid ...

Near infrared spectroscopy is a very promising non-invasive technique since it allows the use of calibration models to monitor physical and chemical properties of raw materials, intermediate products (blend), and the end ...

Pharmaceutical tablets are the most sold and preferred drug solid dosage form due to its many advantages. The feed frame was designed to transfer the powder from the hopper to the tablet press dies as the die disk rotates. ...

This dissertation is focused on understanding the absorption and scattering effects of solid materials in the near infrared (NIR) spectral region and their impact on the prediction errors observed in NIR calibration models ...

This dissertation describes the advancements in Process Analytical Technology (PAT) through developing and implementing strategies for real-time monitoring of drug concentrations in flowing powder blends, analyzing the ...