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Fourier transform infrared mapping to determine the distribution of active ingredients in pharmaceutical formulations
A basic problem in pharmaceutical manufacturing is that a relatively simple formulation can produce widely varying therapeutic performance depending upon how the ingredients are distributed in the final matrix. Many methods ...
Dependence of active mode remote Ft-Ir sensing on angle of incidence, substrate type and analyte surface concentration
A standoff detection scheme for a highly energetic material (HEM) and other threat chemicals deposited on substrates as contamination residues using Fourier transform infrared spectroscopy (FTIR) is described. The HEM used ...
Cleaning validation applications using Mid-Infrared quantum cascade laser spectroscopy
According to the Recall Root Cause Research (RRCR), an initiative governed by the U.S. Food and Drug Administration (FDA), the contamination of pharmaceutical products is an alarming cause of public concern. During 2015, ...