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Development of an empirical model to predict the mean residence time in a tablet press feeder
(2017)
The die filling process is a continuous operation that is crucial to comply with the specifications and quality attributes of a pharmaceutical tablet. Die filling is usually performed using a rotary tablet press that has ...
Effect of operational and design parameters on the early stages of high shear wet granulation processes
(2014)
The development of new technologies, active ingredients and regulatory initiatives, has increased the need for a scientific understanding of the pharmaceutical manufacturing processes. In this context, solid dosage forms ...
Screening soil metagenomic libraries searching for degrading enzymes useful for the production of biofuels and value added chemicals
(2012)
Value-added chemicals and fuels produced via the biotransformation of lignocellulosic biomass resources like crop biomass waste are necessary to reduce our dependence on the non-renewable conversion of raw materials. ...
Electrical characterization of sulfonated poly(styrene-isobutylene-styrene) triblock copolymer thin films
(2015-05)
Polymers are a fundamental part of electronic systems and are widely used due to their low cost, ease of processing, and their wide range of mechanical and electrical properties. They have traditionally been used as passive ...
Experimental and numerical study of the continuous fluidized bed dryer
(2016)
Nowadays, batch fluid-bed drying is one of the most efficient drying methods for particulate material; but at the same time, it is the most energy consuming operation in the manufacturing of solid dosage forms. To minimize ...
Analysis of reaction pathways on the catalytic conversion of CO2 using quantum mechanical calculations
(2015)
The greenhouse gas CO2 is an inexpensive and abundant feedstock that may be used to produce valuable organic compounds. The main goal of this work was to unravel reaction pathways for CO2 conversion through hydrogenation ...
BCS class II drug dispersions in hydroxypropyl methylcellulose solutions: The effect of polymer molecular weight and drug loading on the steady-state rheology of HPMC solutions
(2015)
Physical biopolymer gels are ideal candidates for the drug delivery of solid pharmaceutical drugs. Nevertheless, inclusion of particles may affect the rheology and gelation of these systems. In this work, we evaluate the ...
Transport properties of proton-exchange membranes: effect of supercritical-fluid processing and chemical functionality
(2010)
Nafion® membranes commonly used in direct methanol fuel cells (DMFC), are tipically limited by high methanol permeability (also known as the cross-over limitation). These membranes have phase segregated sulfonated ionic ...
Targeting PDMS hydrophobicity for study of small hydrophobic molecule-driven cell responses in vitro
(2018)
Poly(-dimethyl siloxane) (PDMS) has been the main polymer employed in micro and nano scale devices. Its chemical and physical properties are ideal for molding and soft patterning of microfluidic devices. Despite the great ...
Development of optimized therapeutic platforms for magnetic fluid hyperthermia in adjuvant cancer therapies
(2018-05)
Magnetic Fluid Hyperthermia (MFH) has a great potential as an adjuvant in cancer therapy, enhancing the
effects of antineoplastic agents, sensitizing resistant cancers and reducing undesired side effects. When
compared ...